| 摘要: |
| 目的：探讨卜献春教授诊治不寐的用药规律。方法：收集2022年4月1日至2023年4月30日卜献春教授诊治不寐的门诊处方，运用频数统计、关联规则分析和聚类分析研究其用药规律。结果：共纳入323份处方，涉及239味中药，累计使用频次为7 864次。获得高频药物29味，以安神药、活血药、补血药等为主，药味多为甘、苦、辛，药性多为平、温、微寒，多归于心、肝经。关联规则分析发现核心中药以酸枣仁为基础，搭配地黄、川芎、百合等。聚类分析则发现≥2味中药的聚类方有6类。结论：卜教授治疗不寐的用药多以安神为中心，辅以解郁、养血、活血、滋阴、清热、柔肝、镇静、健脾、化痰等法，重在调心、治肝、敛阳。 |
| 关键词: 不寐 卜献春 数据挖掘 用药规律 |
| DOI： |
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| Medication rule of Bu Xianchun in treatment of insomnia：A study based on data mining |
| LIU Hong,CHEN Bowei,TAN Jun |
| (Hunan University of Chinese Medicine，Changsha 410208，Hunan，China;The First Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410007，Hunan，China;Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine/The Affiliated Hospital of Hunan University of Traditional Chinese Medicine，Changsha 410006，Hunan，China) |
| Abstract: |
| Objective：To investigate the medication rule of Professor Bu Xianchun in the treatment of insomnia.Methods：Related prescriptions were collected from the patients diagnosed and treated by Professor Bu Xianchun at the outpatient service from April 1，2022 to April 30，2023，and frequency statistics，association rule analysis，and cluster analysis were used to investigate the medication rule.Results：A total of 323 prescriptions were included，involving 239 traditional Chinese medicine (TCM) drugs，with a cumulative frequency of use of 7 864 times.A total of 29 high-frequency TCM drugs were obtained，mainly tranquilizing drugs，blood circulation-activating drugs，and blood-replenishing drugs，and most drugs had a sweet，bitter or pungent taste and a neutral，warm or slightly cold nature and mainly entered the heart and liver meridians.The association rule analysis showed that Semen Ziziphi Spinosae was the main core drug and was often used in combination with Radix Rehmanniae，Rhizoma Chuanxiong，and lily.The cluster analysis obtained 6 cluster prescriptions with ≥2 TCM drugs.Conclusion：Professor Bu often uses tranquilizing drugs for the treatment of insomnia，with the assistance of the methods such as resolving stagnation，nourishing the blood，activating blood，nourishing Yin，clearing heat，softening the liver，sedation，strengthening the spleen，and resolving phlegm，while emphasizing heart regulation，liver treatment，and Yang astringing. |
| Key words: insomnia Bu Xianchun data mining medication rule |
