| 摘要: |
| 目的：基于数据挖掘分析《万友生医案选》中治疗外感病处方的用药规律。方法：阅读并筛选《万友生医案选》中外感病相关医案，建立规范化数据库，用中医传承计算平台（V3.5）进行统计学分析。结果：共纳入医案70则，涉及处方70个，有效中药143味，中药累计使用频次761次，高频中药依次为甘草、白芍、白术、麻黄、苦杏仁等。中药种类以补虚类和解表类为主，药性以温、寒为主，药味以甘、苦为主，多归肺、脾、胃经。基于关联规则分析得到14组高频药对，聚类分析得到4个核心药物组合。结论：万友生治疗外感病关注病机的动态变化，注重寒温内外统一，总体上遵循顾护脾胃、甘温除热、扶正祛邪的原则，值得临床借鉴。 |
| 关键词: 外感病 《万友生医案选》 数据挖掘 用药规律 |
| DOI： |
|
|
| Medication rule of Wan Yousheng in treatment of exogenous diseases：A study based on data mining |
| SUN Linyuan,MA Yiwen,YU Xiali |
| (Zhejiang Chinese Medical University，Hangzhou 310053，Zhejiang，China;The First Affiliated Hospital of Zhejiang Chinese Medical University，Hangzhou 310003，Zhejiang，China) |
| Abstract: |
| Objective：To investigate the medication rule of prescriptions in A Selection of Wan Yousheng Medical Records in the treatment of exogenous diseases based on data mining.Methods：The medical records of exogenous diseases in A Selection of Wan Yousheng Medical Records were reviewed and screened to establish a standardized database，and Traditional Chinese Medicine Inheritance Computing System (V3.5) was used for statistical analysis.Results：A total of 70 medical records were included，involving 70 prescriptions and 143 effective traditional Chinese medicine (TCM) drugs，with a cumulative frequency of use of 761 times，and high-frequency TCM drugs included Radix Glycyrrhizae，Radix Paeoniae Alba，Atractylodes macrocephala Koidz.，Ephedrae Herba，and Semen Armeniacae Amarum.Most drugs used were deficiency-tonifying and exterior syndrome-relieving drugs，with a warm or cold nature and a sweet or bitter taste，and they mainly entered the lung，spleen，and stomach meridians.The association rule analysis obtained 14 high-frequency drug combinations，and the cluster analysis obtained 4 core drug combinations.Conclusion：Wan Yousheng pays attention to the dynamic change of pathogenesis during the treatment of exogenous diseases，focuses on the unification of cold and warm evils，and generally follows the principles of taking care of the spleen and the stomach，relieving fever with sweet and warm，and strengthening vital Qi and eliminating pathogens.Therefore，it holds promise for clinical application. |
| Key words: exogenous diseases A Selection of Wan Yousheng Medical Records data mining medication rule |
