| 摘要: |
| 目的：研究60Co-γ辐照灭菌对三七药材质量的影响。方法：采用3个不同60Co-γ辐照剂量（4 kGy、6 kGy、8 kGy）对三七药材进行灭菌处理，通过检测辐照前后三七中人参皂苷Rg1、人参皂苷Rb1、三七皂苷R1含量，辐照前后三七指纹图谱比较、薄层鉴别等，考察不同剂量60Co-γ辐照灭菌对三七药材质量的影响。结果：不同剂量60Co-γ辐照灭菌对三七药材外观、含量、指纹图谱、薄层鉴别影响的差异均无统计学意义。结论：初步表明三七药材灭菌方式可选择60Co-γ辐照进行灭菌。 |
| 关键词: 三七 60Co-γ辐照灭菌 含量 指纹图谱 薄层鉴别 实验研究 |
| DOI： |
|
|
| Influence of 60Co-γ irradiation sterilization on the quality of the medicinal material Panax notoginseng |
| XIAO Man,WU Yan,MA Jiangnan |
| (Hunan Fangsheng Pharmaceutical Co.，Ltd.，Changsha 410205，Hunan，China;Institute of traditional Chinese medicine,Hunan Academy of Chinese Medicine，Changsha 410013，Hunan，China) |
| Abstract: |
| Objective：To investigate the influence of 60Co-γ irradiation sterilization on the quality of the medicinal material Panax notoginseng.Methods：The medicinal material Panax notoginseng was sterilized with 60Co-γ irradiation at three doses (4，6，and 8 kGy).The content of ginsenoside Rg1，ginsenoside Rb1，and notoginsenoside R1 in Panax notoginseng was measured and the fingerprints and thin-layer chromatography (TLC) results of Panax notoginseng were observed before and after irradiation to investigate the influence of different doses of 60Co-γ irradiation sterilization on the quality of Panax notoginseng.Results:There were no significant differences in appearance，content of ingredients，fingerprint，and TLC results between Panax notoginseng treated with 60Co-γ irradiation at different doses.Conclusion：Preliminary results showed that 60Co-γ irradiation can be used as the sterilization method for the medicinal material Panax notoginseng. |
| Key words: Panax notoginseng 60Co-γ irradiation sterilization content fingerprint thin-layer chromatography experimental study |
