| 摘要: |
| 目的：基于“肺与大肠相表里”理论观察督灸治疗脾气虚弱证变应性鼻炎（allergic rhinitis， AR）的临床疗效。方法：将AR脾气虚弱证患者60例随机分为治疗组和对照组，每组各30例。对照组予以鼻用激素联合口服抗组胺药，治疗组在对照组基础上加用督灸治疗，2组均治疗4周。比较治疗前后2组患者的症状、体征评分，过敏性鼻炎生活质量表（Rhinoconjunctivitis Quality of Life Questionnaire，RQLQ）评分，白细胞介素-2（interleukin-2，IL-2）、白细胞介素-4（interleukin-4，IL-4），总免疫球蛋白E（immunoglobulin E，IgE），并评价临床疗效。结果：总有效率2组均为100.00%（30/30），显效率治疗组为33.33%（10/30），对照组为3.33%（1/30），2组显效率比较，差异有统计学意义（P<0.05）。2组症状、体征评分，RQLQ评分，IL-2水平治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P<0.05）。结论：督灸治疗AR脾气虚弱证能改善患者鼻痒、鼻塞、流涕、喷嚏、食少、乏力、便溏等症，降低炎症因子水平，提高生活质量，值得临床推广。 |
| 关键词: 变应性鼻炎 脾气虚弱证 督灸 白细胞介素 临床观察 |
| DOI： |
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| Clinical effect of Du moxibustion in treatment of allergic rhinitis with spleen Qi deficiency: An analysis of 30 cases |
| LIU Xiaofen,WANG Qiu,LI Yanyan,CHEN Baoxiang |
| (Bozhou Hospital of Traditional Chinese Medicine, Bozhou 236800, Anhui, China) |
| Abstract: |
| Objective: To investigate the clinical effect of Du moxibustion in the treatment of allergic rhinitis （AR） with spleen Qi deficiency based on the theory of “the lung and the large intestine being interior-exteriorly related”. Methods: A total of 60 AR patients with spleen Qi deficiency were randomly divided into treatment group and control group, with 30 patients in each group. The patients in the control group received intranasal corticosteroids combined with oral administration of antihistamines, while those in the treatment group received Du moxibustion in addition to the treatment in the control group, and the course of treatment was 4 weeks for both groups. The two groups were compared in terms of symptom and sign scores, Rhinoconjunctivitis Quality of Life Questionnaire （RQLQ） score, and the levels of interleukin-2 （IL-2）, interleukin-4 （IL-4）, and total immunoglobulin E （IgE）, and clinical outcome was assessed. Results: Both groups had an overall response rate of 100.00% （30/30）, and there was a significant difference in marked response rate between the treatment group and the control group ［33.33% （10/30） vs 3.33% （1/30）, P < 0.05］. After treatment, both groups had significant changes in symptom and sign scores, RQLQ score, and the level of IL-2, and there were significant differences in these indicators between the two groups after treatment （P < 0.05）. There were no significant changes in IL-4 and IgE in either group after treatment, with no significant differences between the two groups （P > 0.05）. Conclusion: Du moxibustion for the treatment of AR with spleen Qi deficiency can improve the symptoms such as nasal itching, nasal obstruction, runny nose, sneezing, poor appetite, weakness, and loose stool, reduce the levels of inflammatory factors, and improve quality of life. |
| Key words: allergic rhinitis spleen Qi deficiency Du moxibustion interleukin clinical effect |
