| 摘要: |
| 目的：观察复明片对孔源性视网膜脱离复位硅油填充术后患者视功能恢复的临床疗效。方法：将50 例（50眼）孔源性视网膜脱离复位硅油填充术后患者随机分为治疗组和对照组，每组各25 例（25眼）。对照组予常规妥布霉素地塞米松滴眼液、双氯芬酸钠滴眼液治疗，治疗组在对照组基础上加用复明片口服治疗，疗程均为28 d。观察2组术后7d 、30 d、60 d的最佳矫正视力（BCVA）、眼压以及黄斑区视网膜微结构、视网膜脱离复发率评估临床疗效。结果：术后7 d的总有效率，治疗组为92.00%（23/25），对照组为84.00%（21/25）；术后30 d的总有效率，治疗组为96.00%（24/25），对照组为76.00%（19/25）；术后60 d的总有效率，治疗组为96.00%（24/25），对照组为76.00%（19/25）；组间比较，术后30 d、60 d的总有效率差异有统计学意义(P<0.05)。2组术后7 d、30 d的BCVA均较术前提高，且治疗组高于对照组，差异有统计学意义（P<0.05）。2组眼压及黄斑区视网膜微结构术前术后组内比较和术后7 d、30 d、60 d 组间比较，差异均无统计学意义(P>0.05)。随访期间，2组患者均未出现视网膜脱离复发情况。结论：在常规西药治疗基础上加服复明片有助于视网膜脱离复位术后患者视功能的恢复，值得临床推广。 |
| 关键词: 孔源性视网膜脱离 硅油填充 中医药疗法 复明片 |
| DOI： |
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| Clinical effect of Fuming tablets on recovery of visual function after silicone oil tamponade for rhegmatogenous retinal detachment repair |
| LUO Yanhua,LI Jingyi,GU Pengtao |
| (Department of Ophthalmology，Guangdong Provincial Hospital of Traditional Chinese Medicine，Guangzhou 510120，Guangdong，China;Department of Ophthalmology，Zhujiang Hospital of Southern Medical University，Guangzhou 510145，Guangdong，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Fuming tablets on the recovery of visual function after silicone oil tamponade for rhegmatogenous retinal detachment repair.Methods：A total of 50 patients (50 eyes) who received silicone oil tamponade for rhegmatogenous retinal detachment repair were randomly divided into treatment group and control group，with 25 patients (25 eyes) in each group.The patients in the control group were given tobramycin dexamethasone eye drops and diclofenac sodium eye drops，and those in the treatment group were given oral administration of Fuming tablets in addition to the treatment in the control group.The course of treatment was 28 days for both groups.The two groups were observed in terms of best corrected visual acuity (BCVA)，intraocular pressure，retinal microstructure in the macular region，and the recurrence rate of retinal detachment on days 7，30，and 60 after surgery，and clinical outcome was assessed for both groups.Results：The overall response rate on day 7 after surgery was 92.00% (23/25) in the treatment group and 84.00% (21/25) in the control group，and there was a significant difference in overall response rate between the treatment group and the control group on days 30 and 60 after surgery ［day 30：96.00% (24/25) vs 76.00% (19/25)，P<0.05；day 60：96.00% (24/25) vs 76.00% (19/25)，P<0.05］.Both groups had a significant increase in BCVA on days 7 and 30 after surgery，and the treatment group had a significantly higher BCVA than the control group (P<0.05).There were no significant changes in intraocular pressure and retinal microstructure in the macular region in either group after surgery，and there were no significant differences in these indicators between the two groups on days 7，30，and 60 after surgery (P>0.05).No recurrence of retinal detachment was observed in either group during follow-up.Conclusion：Oral administration of Fuming tablets in addition to conventional Western medicine treatment can help with the recovery of visual function after surgery for retinal detachment repair，and therefore，it holds promise for clinical application. |
| Key words: rhegmatogenous retinal detachment silicone oil tamponade traditional Chinese medicine treatment Fuming tablets |
