| 摘要: |
| 目的：观察刺络放血联合自制伤痛散外敷对急性痛风性关节炎的临床疗效。方法：将50 例急性痛风性关节炎患者随机分为治疗组和对照组，每组各25 例。对照组予以塞来昔布胶囊治疗，治疗组在对照组治疗的基础上予以刺络放血联合自制伤痛散外敷治疗。比较2组中医证候积分、视觉模拟量表(visual analogue scale，VAS)评分、血尿酸（uric acid，UA）水平、红细胞沉降率(erythrocyte sedimentation rate，ESR)、C反应蛋白(C-reactive protein，CRP)水平及不良反应发生情况。结果：总有效率治疗组为92.00%（23/25），对照组为76.00%（19/25），2组比较，差异有统计学意义（P＜0.05）。治疗后2组VAS评分，血UA水平、ESR及CRP水平均有所改善，且治疗组改善幅度大于对照组（P＜0.05）;因2组均有内服非甾体镇痛消炎药，治疗组有1 例患者出现胃痛，对照组有2 例患者出现胃痛、恶心，停药后症状均缓解，暂未见外用药物所致的不良反应。结论：刺络放血联合自制伤痛散外敷治疗急性痛风性关节炎临床疗效显著，能有效缓解症状，且无明显不良反应，值得临床推广。 |
| 关键词: 急性痛风性关节炎 刺络放血 自制伤痛散 外敷 VAS 血UA ESR CRP |
| DOI： |
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| Clinical effect of blood-letting puncture combined with external application with self-made Shangtong powder in treatment of acute gouty arthritis：An analysis of 25 cases |
| LI Wenya,WEN Bin,HU Chang |
| (The Air Force Hospital of Southern Theater Command，Guangzhou 510030，Guangdong，China) |
| Abstract: |
| Objective：To investigate the clinical effect of blood-letting puncture combined with external application with self-made Shangtong powder in the treatment of acute gouty arthritis.Methods：A total of 50 patients with acute gouty arthritis were randomly divided into treatment group and control group，with 25 patients in each group.The patients in the control group received celecoxib capsules，and those in the treatment group received blood-letting puncture combined with external application with self-made Shangtong powder in addition to the treatment in the control group.The two groups were compared in terms of traditional Chinese medicine syndrome score，visual analogue scale (VAS) score，serum uric acid (UA)，erythrocyte sedimentation rate (ESR)，C-reactive protein (CRP)，and adverse reactions.Results：There was a significant difference in overall response rate between the treatment group and the control group ［92.00%(23/25)vs76.00%(19/25)，P＜0.05］.After treatment，both groups had improvements in VAS score，serum UA，ESR，and CRP，and the treatment group had significantly greater improvements than the control group (P＜0.05).Due to the oral administration of non-steroidal analgesic anti-inflammatory drug，1 patient in the treatment group experienced stomachache，while 2 patients in the control group experienced stomachache and nausea，and these symptoms were relieved after drug withdrawal.Adverse reactions due to the drug for external application were not observed.Conclusion：Blood-letting puncture combined with external application with self-made Shangtong powder has a marked clinical effect in the treatment of acute gouty arthritis and can effectively alleviate symptoms without obvious adverse reactions，and therefore，it holds promise for clinical application. |
| Key words: acute gouty arthritis blood-letting puncture self-made Shangtong powder external application Visual Analogue Scale uric acid erythrocyte sedimentation rate C-reactive protein |
