| 摘要: |
| 目的：观察复方三叶香茶菜片治疗低病毒载量慢性乙型肝炎（CHB）湿热内结证的临床疗效。方法：收集符合纳入标准的30 例低病毒载量CHB湿热内结证患者的临床资料，并进行回顾性总结，比较患者治疗前后肝功能［总胆红素（TBIL）、丙氨酸转氨酶（ALT）、天冬氨酸转氨酶（AST）、白球比（A/G）］及肝脏瞬时弹性硬度［肝硬度值（LSM）、受控衰减参数（CAP）］，和治疗前、治疗3个月、治疗6个月、治疗9个月的乙型肝炎病毒脱氧核糖核酸（HBV-DNA）水平。结果：治疗后患者的肝功能各项指标及LSM值均较治疗前下降（P<0.01），其CAP值虽低于治疗前，但差异无统计学意义（P＞0.05）；治疗3个月、6个月、9个月的HBV-DNA水平均较治疗前降低（P<0.01）。结论：复方三叶香茶菜片治疗低病毒载量CHB湿热内结证具有良好的临床疗效，值得临床推广应用。 |
| 关键词: 慢性乙型肝炎 复方三叶香茶菜片 湿热内结证 低病毒载量 HBV-DNA |
| DOI： |
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| Clinical effect of Compound Sanye Xiangchacai Tablet in treatment of chronic hepatitis B with low viral load and damp-heat internal syndrome：An analysis of 30 cases |
| QIN Renjie,CHEN Peng,WU Zhipeng |
| (Guangxi University of Chinese Medicine，Nanning 530200，Guangxi，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Compound Sanye Xiangchacai Tablet in the treatment of chronic hepatitis B (CHB) with low viral load and damp-heat internal syndrome.Methods：A retrospective analysis was performed for the clinical data of 30 CHB patients with low viral load and damp-heat internal syndrome who met the inclusion criteria，and the patients were compared in terms of liver function ［total bilirubin （TBIL），alanine aminotransferase （ALT），aspartate aminotransferase （AST），and albumin/globulin ratio （A/G）］ and transient liver stiffness ［liver stiffness measurement （LSM） and controlled attenuation parameter （CAP）］ before and after treatment，as well as HBV-DNA level before treatment and at 3，6，and 9 months of treatment.Results：After treatment，there were significant reductions in the above liver function parameters and LSM (P<0.01) and a reduction in CAP (P>0.05).HBV-DNA level at 3，6，and 9 months of treatment was significantly lower than that before treatment (P<0.01).Conclusion：Compound Sanye Xiangchacai Tablet has a good clinical effect in the treatment of CHB with low viral load and damp-heat internal syndrome and thus holds promise for clinical application. |
| Key words: chronic hepatitis B Compound Sanye Xiangchacai Tablet damp-heat internal syndrome low viral load HBV-DNA |
