| 摘要: |
| 目的：观察芪术增液汤治疗气阴两虚型慢传输型便秘（STC)的临床疗效。方法：将70 例气阴两虚型STC患者随机分为治疗组和对照组，每组各35 例。治疗组予芪术增液汤治疗，对照组予枸橼酸莫沙必利片治疗。治疗28 d后比较2组综合疗效、排便评分（排便间隔时间、排便费力程度、粪便性状、排便时间）、中医证候（气短乏力、神疲懒言、口干少津、头晕耳鸣）积分及复发率。结果：总有效率治疗组为91.43%（32/35），对照组为71.43%（25/35），组间比较，差异有统计学意义（P＜0.05）。排便各项指标评分、各项中医证候评分治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P＜0.05）。复发率治疗组为12.50%（4/32），对照组为36.00%（9/25），2组比较，差异有统计学意义（P＜0.05）。结论：芪术增液汤治疗气阴两虚型STC疗效确切，复发率低，值得临床推广应用。 |
| 关键词: 慢传输型便秘 气阴两虚型 中医药疗法 芪术增液汤 |
| DOI： |
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| Clinical effect of Qizhu Zengye decoction in treatment of slow transit constipation with deficiency of both Qi and Yin：An analysis of 35 cases |
| YANG Ting,PI Mao |
| (Xiangtan Hospital of Traditional Chinese Medicine，Xiangtan 411100，Hunan，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Qizhu Zengye decoction in the treatment of slow transit constipation (STC) with deficiency of both Qi and Yin.Methods：A total of 70 STC patients with deficiency of both Qi and Yin were randomly divided into treatment group and control group，with 35 patients in each group.The patients in the treatment group were given Qizhu Zengye decoction，and those in the control group were given mosapride citrate tablets.After 28 days of treatment，the two groups were compared in terms of overall response，defecation scores (defecation interval，degree of difficult defecation，stool form，and defecation time)，scores of traditional Chinese medicine (TCM) syndromes (short breath and weakness，fatigue and laziness to speak，dry mouth with little saliva，and dizziness and tinnitus)，and recurrence rate.Results：There was a significant difference in overall response rate between the treatment group and the control group ［91.43% (32/35) vs 71.43% (25/35)，P＜0.05］.Both groups had significant changes in defecation scores and TCM syndrome scores after treatment，and there were significant differences in these scores between the two groups after treatment (P＜0.05).There was a significant difference in recurrence rate between the treatment group and the control group ［12.50% (4/32) vs 36.00% (9/25)，P＜0.05］.Conclusion：Qizhu Zengye decoction has a marked clinical effect and a low recurrence rate in the treatment of STC with deficiency of both Qi and Yin and thus holds promise for clinical application. |
| Key words: slow transit constipation deficiency of both Qi and Yin traditional Chinese medicine treatment Qizhu Zengye decoction |
