| 摘要: |
| 目的：观察痛风方联合吲哚美辛治疗湿热蕴结型痛风的临床疗效。方法：将120例湿热郁结型痛风患者随机分为治疗组和对照组，每组各60例。治疗组采用痛风方联合吲哚美辛治疗，对照组单用吲哚美辛治疗。治疗2周后评定2组综合疗效，并比较2组治疗前后中医证候积分、白细胞（WBC）、血清尿酸（UA）、红细胞沉降率（ESR）、C-反应蛋白（CRP）水平。结果：总有效率治疗组为95.00%（57/60），对照组为81.67%（49/60），组间比较，差异有统计学意义（P＜0.05）；中医证候积分及UA、ESR、CRP水平治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P＜0.05）；WBC水平治疗前后组内比较，差异有统计学意义（P＜0.05），但治疗后组间比较，差异无统计学意义（P>0.05）。结论：痛风方联合吲哚美辛能改善湿热蕴结型痛风患者的中医症状，降低WBC、UA、ESR、CRP水平，且不良反应少。 |
| 关键词: 痛风 湿热蕴结型 中西医结合疗法 痛风方 |
| DOI： |
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| Clinical effect of Tongfeng prescription combined with indomethacin in treatment of gout with damp-heat accumulation：An analysis of 60 cases |
| YANG Qiaoyu,MAO Yiping,CHEN Yanqiao |
| (The Third Peoples Hospital of Dongguan，Dongguan 410208，Guangdong，China;The Second Peoples Hospital of Changde，Changde 415000，Hunan，China;The Second Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410005，Hunan，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Tongfeng prescription combined with indomethacin in the treatment of gout with damp-heat accumulation.Methods：A total of 120 patients with gout with damp-heat accumulation were randomly divided into treatment group and control group，with 60 patients in each group.The patients in the treatment group were given Tongfeng prescription combined with indomethacin，and those in the control group were given indomethacin alone.Overall response was evaluated after 2 weeks of treatment，and the two groups were compared in terms of traditional Chinese medicine (TCM) syndrome score，white blood cell count (WBC)，serum uric acid (UA)，erythrocyte sedimentation rate (ESR)，and C-reactive protein (CRP) before and after treatment.Results：There was a significant difference in overall response rate between the treatment group and the control group [95.00% (57/60) vs 81.67% (49/60)，P＜0.05].Both groups had significant changes in TCM syndrome，UA，EAR，and CRP after treatment，and there were significant differences in these indices between the two groups after treatment (P＜0.05).Both groups had a significant change in WBC after treatment (P＜0.05)，and there was no significant difference in WBC between the two groups after treatment (P>0.05).Conclusion：In the treatment of gout with damp-heat accumulation，Tongfeng prescription combined with indomethacin can significantly improve patients’ TCM symptoms and reduce WBC，UA，ESR，and CRP，with few adverse reactions. |
| Key words: gout damp-heat accumulation integrated traditional Chinese and Western medicine therapy Tongfeng prescription |
