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基于数据挖掘分析《类证治裁》治疗脾胃病的用药规律
杨远航,蔡佳丽
0
(天津中医药大学,天津,301617)
摘要:
目的:基于数据挖掘分析林珮琴《类证治裁》治疗脾胃病的用药规律,为中医药治疗脾胃病及新方研发提供参考。方法:运用中医传承计算平台构建《类证治裁》治疗脾胃病的方剂数据库,并对其进行用药频次、性味、归经、功效、高频组合与核心组合的分析。结果:共纳入方剂123首,涉及药物142味。用药频次≥20次的共8味,其中甘草应用频次最多。四气以温、寒、平为主,五味以甘、苦、辛为主,归经以脾、肺、胃为主。药物功效以补虚类为主。通过关联规则分析得到药物高频组合16组,通过聚类分析得到药物核心组合3组。结论:林珮琴治疗脾胃病始终秉持“以补益脾胃为本”的理念,补行并重,补清兼顾,为现代中医学诊治脾胃病提供了一定的理论依据。
关键词:  《类证治裁》  脾胃病  数据挖掘  用药规律
DOI:
Medication rule of the treatment of spleen and stomach diseases in Classified Treatments Based on Categorical Identification: A study based on data mining
YANG Yuanhang,CAI Jiali
(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)
Abstract:
Objective: To analyse the medication rule of the treatment of spleen and stomach diseases in Classified Treatments Based on Categorical Identification by Lin Peiqin,and to provide a reference for the traditional Chinese medicine (TCM) treatment of spleen and stomach diseases and the development of new prescriptions.Methods: Traditional Chinese Medicine Inheritance Computing System was used to establish a database of the prescriptions for the treatment of spleen and stomach diseases in Classified Treatments Based on Categorical Identification,and analyses were performed for drug use frequency,nature and taste,meridian entry,function,high-frequency combinations,and core combinations.Results: A total of 123 prescriptions were included,involving 142 TCM drugs.There were 8 drugs with a frequency of use of ≥20 times,among which Radix Glycyrrhizae had the highest frequency of use.Most drugs had a warm,cold or neutral nature and a sweet,bitter or pungent taste,and they mainly entered the spleen,lung,and stomach meridians.Most drugs had the function of tonifying deficiency.The association rule analysis obtained 16 high-frequency drug combinations,and the cluster analysis obtained 3 core drug combinations.Conclusion: In the treatment of spleen and stomach diseases,Lin Peiqin adhered to the concept of “tonifying the spleen and stomach as the foundation of treatment”,emphasizing both tonifying and promoting and giving consideration to both tonifying and clearing,which provides a certain theoretical basis for the diagnosis and treatment of spleen and stomach diseases by modern TCM technology.
Key words:  Classified Treatments Based on Categorical Identification  spleen and stomach diseases  data mining  medication rule

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