| 摘要: |
| 目的：探讨中医综合疗法治疗子宫腺肌病痛经的临床疗效。方法：将80 例子宫腺肌病痛经患者随机分为治疗组和对照组，每组各40 例。治疗组给予中医综合疗法（中药口服、中药离子导入以及中药灌肠）治疗，对照组给予口服孕三烯酮治疗，治疗3个月经周期后，观察比较2组痛经疼痛视觉模拟量表（VAS）评分、月经量月经失血图（PBAC）评分、子宫体积，血清糖类抗原125（CA125）、卵泡雌激素（FSH）、促黄体生长素（LH）、血中性粒细胞/淋巴细胞比值(NLR)以及C-反应蛋白 (CRP)水平。结果：2组痛经VAS评分、月经量PBAC评分、CA125、FSH、LH、NLR水平均下降，子宫体积均缩小，CRP水平均上升，且治疗组改善幅度较对照组大，差异均有统计学意义（均P＜0.05）。结论：中药口服配合中药离子导入以及中药灌肠疗法可以缓解子宫腺肌病痛经症状，降低肿瘤标志物等血清学指标水平，减轻体内炎症反应，保护卵巢功能，具有良好的临床应用价值。 |
| 关键词: 子宫腺肌病 痛经 中医药疗法 口服 离子导入 灌肠 |
| DOI： |
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| Clinical effect of integrated traditional Chinese medicine therapy in treatment of adenomyosis dysmenorrhea：An analysis of 40 cases |
| LIU Derong |
| (Linyi Hospital of Traditional Chinese Medicine，Linyi 276003，Shandong，China) |
| Abstract: |
| Objective：To investigate the clinical effect of integrated traditional Chinese medicine therapy in the treatment of adenomyosis dysmenorrhea.Methods：A total of 80 patients with adenomyosis dysmenorrhea were randomly divided into treatment group and control group，with 40 patients in each group.The patients in the treatment group were given integrated traditional Chinese medicine therapy (oral administration，iontophoresis，and traditional Chinese medicine enema)，and those in the control group were given the oral administration of gestrinone.After treatment for three menstrual cycles，the two groups were observed and compared in terms of Visual Analogue Scale (VAS) score for dysmenorrhea，Pictorial Blood Loss Assessment Chart (PBAC) score for menstrual volume，uterine volume，and the serum levels of carbohydrate antigen 125 (CA125)，follicle-stimulating hormone (FSH)，luteinizing hormone (LH)，neutrophil-lymphocyte ratio (NLR)，and C-reactive protein (CRP).Results：Both groups had significant reductions in VAS score for dysmenorrhea，PBAC score for menstrual volume，uterine volume，and the levels of CA125，FSH，LH，and NLR，as well as a significant increase in the level of CRP，and the treatment group had significantly greater improvements than the control group (all P＜0.05).Conclusion：Oral administration of traditional Chinese medicine combined with iontophoresis and traditional Chinese medicine enema can alleviate the symptoms of adenomyosis dysmenorrhea，reduce the levels of serological markers including tumor markers，reduce inflammatory response in the body，and protect ovarian function，with a good clinical application value. |
| Key words: adenomyosis dysmenorrhea traditional Chinese medicine treatment oral administration iontophoresis enema |
