| 摘要: |
| 目的：探讨健脾固妊汤治疗脾胃虚弱型妊娠呕吐的临床疗效。方法：将60 例脾胃虚弱型妊娠呕吐患者按照随机数字表法分为治疗组和对照组，每组各30 例。对照组予西医常规治疗，治疗组在对照组治疗的基础上配合健脾固妊汤治疗。比较2 组临床疗效、血清胃泌素（GAS）含量、血清血管活性肠肽（VIP）含量、尿酮体转阴时间、住院时间以及安全性。结果：治愈率治疗组为80.00%（24/30），对照组为70.00%（21/30），差异有统计学意义（P<0.05）。治疗后，2组GAS和VIP水平均显著下降，且治疗组下降幅度更大，差异均有统计学意义（P<0.01或P<0.05）。治疗组尿酮体转阴时间、住院时间均短于对照组，差异有统计学意义(P<0.01)。2组治疗过程中均未出现明显的不良反应。结论：健脾固妊汤联合西药治疗脾胃虚弱型妊娠呕吐疗效颇佳，值得临床推广应用。 |
| 关键词: 妊娠呕吐 脾胃虚弱型 中西医结合疗法 健脾固妊汤 |
| DOI： |
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| Clinical effect of Jianpi Guren decoction in treatment of vomiting of pregnancy with deficiency of spleen and stomach：An analysis of 30 cases |
| ZHU Shuangquan,HE Bing,WANG Ping |
| (The Second Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410005，Hunan，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Jianpi Guren decoction in the treatment of vomiting of pregnancy with deficiency of spleen and stomach.Methods：A total of 60 patients with vomiting of pregnancy with deficiency of spleen and stomach were divided into treatment group and control group using a random number table，with 30 patients in each group.The patients in the control group were given conventional Western medicine treatment，and those in the treatment group were given Jianpi Guren decoction in addition to the treatment in the control group.The two groups were compared in terms of clinical outcome，serum gastrin (GAS) content，serum vasoactive intestinal peptide (VIP) content，time to clearance of urine acetone bodies，length of hospital stay，and safety.Results：There was a significant difference in cure rate between the treatment group and the control group ［80.00% (24/30) vs 70.00% (21/30)，P<0.05］.After treatment，both groups had significant reductions in GAS and VIP，and the treatment group had significantly greater reductions than the control group (P<0.01 or P<0.05).Compared with the control group，the treatment group had significantly shorter time to clearance of urine acetone bodies and length of hospital stay (P<0.01).There were no obvious adverse reactions in either group during treatment.Conclusion：Jianpi Guren decoction combined with Western medicine treatment has a marked clinical effect in the treatment of vomiting of pregnancy with deficiency of spleen and stomach and thus holds promise for clinical application. |
| Key words: vomiting of pregnancy deficiency of spleen and stomach integrated traditional Chinese and Western medicine therapy Jianpi Guren decoction |
