| 摘要: |
| 目的：观察中药足浴联合西医常规疗法治疗糖尿病周围神经病变的临床疗效。方法：将104 例糖尿病周围神经病变患者随机分为治疗组和对照组，每组各52 例。对照组给予西医常规疗法，治疗组在对照组基础上联合中药足浴治疗，2组疗程均为4周。比较2组治疗前后的空腹血糖（FPG）、C反应蛋白（CRP）、多伦多（Toronto）评分、感觉神经传导速度（SNCV）、运动神经传导速度（MNCV）、中医证候评分，评定中医证候疗效。结果：总有效率治疗组为80.8%（42/52），对照组为9.6%（5/52），2组比较，差异有统计学意义（P＜0.01）。治疗后治疗组CRP、Toronto评分及中医证候评分较治疗前均明显降低，且低于对照组治疗后，差异有统计学意义（P＜0.05）。2组治疗后SNCV、MNCV均较治疗前提高（P＜0.05），且治疗组提高幅度更大（P＜0.01）。结论：中药足浴联合西医常规疗法治疗可减轻糖尿病周围神经病变患者的炎症反应，提高神经传导速度，改善临床症状，值得临床推广运用。 |
| 关键词: 糖尿病周围神经病变 中药足浴 甲钴胺胶囊 |
| DOI： |
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| Clinical effect of traditional Chinese medicine foot bath combined with conventional Western medicine therapy in treatment of diabetic peripheral neuropathy：An analysis of 52 cases |
| YU Jinxin,LIU Chunhui,XIA Wei |
| (Qidong Hospital of Traditional Chinese Medicine，Qidong 226200，Jiangsu，China) |
| Abstract: |
| Objective：To investigate the clinical effect of traditional Chinese medicine (TCM) foot bath combined with conventional Western medicine therapy in the treatment of diabetic peripheral neuropathy.Methods：A total of 104 patients with diabetic peripheral neuropathy were randomly divided into treatment group and control group，with 52 patients in each group.The patients in the control group were given conventional Western medicine therapy，while those in the treatment group were given TCM foot bath in addition to the treatment in the control group，and the course of treatment was 4 weeks for both groups.The two groups were compared in terms of fasting plasma glucose (FPG)，C-reactive protein (CRP)，Toronto score，sensory nerve conduction velocity (SNCV)，motor nerve conduction velocity (MNCV)，and TCM syndrome score before and after treatment，and the treatment outcome of TCM syndrome was evaluated.Results：There was a significant difference in overall response rate between the treatment group and the control group ［80.8% (42/52) vs 9.6% (5/52)，P<0.01］.After treatment，the treatment group had significant reductions in CRP，Toronto score，and TCM syndrome score，which were significantly lower than those in the control group (P<0.05).After treatment，both groups had significant increases in SNCV and MNCV (P<0.05)，and the treatment group had significantly greater increases than the control group (P<0.01).Conclusion：In patients with diabetic peripheral neuropathy，TCM foot bath combined with conventional Western medicine therapy can alleviate inflammatory response，increase nerve conduction velocity，and improve clinical symptoms，and therefore，it holds promise for clinical application. |
| Key words: diabetic peripheral neuropathy traditional Chinese medicine foot bath mecobalamin capsules |
