| 摘要: |
| 目的：观察中药麻仁丸联合生物反馈治疗功能性便秘的临床疗效。方法：选取初诊的功能性便秘患者60 例，将其随机分为2组，每组各30 例。治疗组采用中药麻仁丸口服联合生物反馈治疗，对照组仅口服麻仁丸治疗，2组疗程均为28 d。观察2组生活质量量表（PAC-QOL）评分、临床症状评分、盆底肌电评估测量值，并进行疗效评价。结果：总有效率治疗组为90.00%（27/30），对照组为83.33%（25/30），2组比较，差异有统计学意义（P<0.05）；2组PAC-QOL评分治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P<0.01）；2组治疗2、4周以及治疗结束后2周各项症状体征评分与本组治疗前比较，差异均有统计学意义（P＜0.05）；2组排便时间、腹胀积分比较，治疗组在治疗4周及治疗结束后2周均低于对照组（P＜0.01或P＜0.05）；2组下坠、不尽、胀感及排便频度积分比较，治疗组在治疗2、4周及治疗结束后2周均低于对照组（P＜0.05或P＜0.01）；治疗组治疗前后盆底肌电评估测量值差异有统计学意义（P＜0.01）。结论：中药麻仁丸联合生物反馈治疗功能性便秘较单用麻仁丸治疗效果更好。 |
| 关键词: 功能性便秘 生物反馈 盆底肌电评估 麻仁丸 |
| DOI： |
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| Clinical effect of the traditional Chinese medicine Maren pills combined with biofeedback therapy in treatment of functional constipation：An analysis of 30 cases |
| ZHANG Hua,ZHANG Danfeng,HE Cifen |
| (Shanghai Jinshan Hospital of Integrated Traditional Chinese and Western Medicine，Shanghai 201501，China) |
| Abstract: |
| Objective：To investigate the clinical effect of the traditional Chinese medicine Maren pills combined with biofeedback therapy in the treatment of functional constipation.Methods：A total of 60 patients with functional constipation at initial diagnosis were selected and randomly divided into treatment group and control group，with 30 patients in each group.The patients in the treatment group were given oral administration of Maren pills combined with biofeedback therapy，while those in the control group were given oral administration of Maren pills alone，and the course of treatment was 28 days for both groups.The two groups were observed in terms of Patient Assessment of Constipation Quality of Life Questionnaire (PAC-QOL) score，clinical symptom score，and measured values of pelvic floor electromyography，and treatment outcome was evaluated.Results：There was a significant difference in overall response rate between the treatment group and the control group ［90.00% (27/30) vs 83.33% (25/30)，P<0.05］.Both groups had a significant change in PAC-QOL score after treatment，and there was a significant difference in PAC-QOL score between the two groups after treatment (P<0.01).Both groups had significant changes in the scores of symptoms and signs at weeks 2 and 4 of treatment and at 2 weeks after treatment (P<0.05).Compared with the control group，the treatment group had significantly lower scores of defecation time and abdominal distension at week 4 of treatment and at 2 weeks after treatment (P<0.01 or P<0.05)，as well as significantly lower scores of tenesmus，incomplete defecation，feeling of distension，and defecation frequency at weeks 2 and 4 of treatment and at 2 weeks after treatment (P<0.05 or P<0.01).The treatment group had significant changes in the measured values of pelvic floor electromyography after treatment (P<0.01).Conclusion：The traditional Chinese medicine Maren pills combined with biofeedback therapy has a better clinical effect than Maren pills alone in the treatment of functional constipation. |
| Key words: functional constipation biofeedback pelvic floor electromyography Maren pills |
