| 摘要: |
| 目的：观察扶阳方治疗缺血性中风（IS）恢复期阳虚证的临床疗效，并探讨其作用机制。方法：将50 例IS恢复期阳虚证患者随机分为治疗组和对照组，每组各25 例。2组均予以基础治疗，在此基础上治疗组加用扶阳方治疗，对照组加用补阳还五汤治疗，2组均治疗28 d。观察2组治疗前、治疗14 d后、治疗28 d后日常生活活动能力（ADL）评分、美国国立卫生研究院卒中量表（NIHSS）评分、生活质量评分、中医证候积分及安全性，并评价临床疗效。结果：总有效率治疗组为92.00%（23/25），对照组为76.00%(19/25)，2组比较，差异有统计学意义（P＜0.05）；2组ADL评分、NIHSS评分、生活质量评分、中医证候积分治疗前后组内比较及治疗后同时间节点组间比较，差异均有统计学意义（P＜0.05或P＜0.01）；2组治疗前后血常规、大便常规、尿常规及肝肾功能均未出现明显改变。结论：扶阳方治疗IS恢复期阳虚证疗效确切，明显优于补阳还五汤，为运用中医扶阳理论治疗IS恢复期提供了临床证据。 |
| 关键词: 缺血性中风恢复期 扶阳方 补阳还五汤 |
| DOI： |
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| Clinical effect of Fuyang prescription in treatment of the convalescence stage of ischemic stroke：An analysis of 25 cases |
| WEI Menghua,MEI Xiaoping,MO Xueni |
| (Wei’s Traditional Chinese Medicine Clinic，Bose 542899，Guangxi，China;Guangxi International Zhuang Medicine Hospital，Nanning 530023，Guangxi，China;Guangxi University of Chinese Medicine，Nanning 530001，Guangxi，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Fuyang prescription in the treatment of the convalescence stage of ischemic stroke (IS) with Yang deficiency and its mechanism of action.Methods：A totalof 50 patients in the convalescence stage of IS with Yang deficiency were randomly divided into treatment group and control group，with 25 patients in each group.The patients in the treatment group were given basic treatment combined with Fuyang prescription，and those in the control group were given basic treatment combined with Buyang Huanwu decoction；the course of treatment was 28 days for both groups.The two groups were observed in terms of Activities of Daily Living (ADL) score，National Institutes of Health Stroke Scale (NIHSS) score，quality of life score，TCM syndrome score，and safety before treatment and after 14 and 28 days of treatment，and clinical outcome was evaluated for both groups.Results：There was a significant difference in overall response rate between the treatment group and the control group ［92.00%(23/25) vs 76.00%(19/25)，P<0.05］.After treatment，both groups had significant changes in ADL score，NIHSS score，quality of life score，and TCM syndrome score，and there were significant differences in these indices between the two groups at the same time point after treatment (P＜0.05 or P＜0.01).There were no significant changes in routine blood test results，routine stool test results，routine urine test results，and liver/renal function in either group after treatment.Conclusion：Fuyang prescription has a marked clinical effect in the treatment of the convalescence stage of IS with Yang deficiency，with a significantly better clinical effect than Buyang Huanwu decoction，which provides clinical evidence for the traditional Chinese medicine theory of Yang supporting in the treatment of the convalescence stage of IS. |
| Key words: convalescence stage of ischemic stroke Fuyang prescription Buyang Huanwu decoction |
