| 摘要: |
| 目的：观察瓜蒌薤白半夏汤加减改善冠心病患者心功能的临床疗效。方法：选取缺血性心肌病型冠心病痰浊痹阻证患者84 例，将其分为治疗组和对照组，每组各42 例。2组均予以阿司匹林治疗，在此基础上治疗组加用瓜蒌薤白半夏汤加减治疗，对照组加用单硝酸异山梨酯片治疗。2组治疗前后均进行组织多普勒（TDI）收缩期峰值Sa参数及Tei指数参数测定，并观察其改善情况。结果：用药前2组各节段TDI收缩期峰值Sa及Tei指数比较，差异无统计学意义（P>0.05）；2组各节段TDI收缩期峰值Sa及Tei指数治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P＜0.05）。结论：阿司匹林联合瓜蒌薤白半夏汤加减可明显改善缺血性心肌病型冠心病痰浊痹阻证患者的心功能指标，其疗效优于阿司匹林联合单硝酸异山梨酯片治疗。 |
| 关键词: 冠心病 心功能 瓜蒌薤白半夏汤 组织多普勒 Tei指数 |
| DOI： |
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| Clinical effect of modified Gualou Xiebai Banxia decoction in improving cardiac function in patients with coronary heart disease：An analysis of 42 cases |
| WANG Sijia,WANG Yueai,CHEN Xiaoqiong |
| (The First Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410007，Hunan，China) |
| Abstract: |
| Objective：To investigate the clinical effect of modified Gualou Xiebai Banxia decoction in improving cardiac function in patients with coronary heart disease.Methods：A total of 84 coronary heart disease patients with ischemic cardiomyopathy with phlegm-turbidity obstruction syndrome were enrolled and divided into treatment group and control group，with 42 patients in each group.In addition to aspirin，the patients in the treatment group were given modified Gualou Xiebai Banxia decoction，and those in the control group were given isosorbide mononitrate tablets.Tissue Doppler imaging was performed for both groups before and after treatment to measure the peak systolic velocity Sa and myocardial performance index (Tei index) and observe their improvement.Results：Before treatment，there were no significant differences in the peak systolic velocity Sa and Tei index of each segment between the two groups (P>0.05)；after treatment，both groups had significant changes in the peak systolic velocity Sa and Tei index of each segment，and there were significant differences between the two groups (P＜0.05).Conclusion：In coronary heart disease patients with ischemic cardiomyopathy with phlegm-turbidity obstruction syndrome，aspirin combined with modified Gualou Xiebai Banxia decoction can significantly improve cardiac function and has a better clinical effect than aspirin combined with isosorbide mononitrate tablets. |
| Key words: coronary heart disease cardiac function Gualou Xiebai Banxia decoction tissue Doppler imaging myocardial performance index |
