| 摘要: |
| 目的：观察仙蓉养精种玉汤对多囊卵巢综合征（PCOS）肾阴亏虚证患者的临床疗效。方法：选取肾阴亏虚型PCOS患者60例，采用随机数字表法将其分为治疗组与对照组，每组各30例。治疗组予以仙蓉养精种玉汤治疗，对照组予以达英-35治疗，2组均治疗3个月经周期，观察2组患者卵泡发育、排卵情况、临床疗效、中医证候积分及血清性激素水平的变化。结果：总有效率治疗组为90.00%，对照组为73.33%，2组比较，差异有统计学意义（P<0.05）；2组患者中医证候积分，排卵情况，血清T、LH、LH/FSH水平等指标治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P<0.05）；治疗组治疗后对月经周期、经量、卵泡发育的改善效果均优于对照组，差异有统计学意义（P<0.05）。结论：仙蓉养精种玉汤治疗肾阴亏虚型PCOS临床疗效显著，安全性高，同时在调节性激素水平、改善患者临床症状、促进卵泡发育及排卵方面具有促进作用。 |
| 关键词: 多囊卵巢综合征 肾阴亏虚证 中医药疗法 仙蓉养精种玉汤 |
| DOI： |
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| Clinical effect of Xianrong Yangjing Zhongyu decoction in treatment of polycystic ovary syndrome with kidney Yin deficiency：An analysis of 30 cases |
| WANG Wenpeng,FANG Yi,MO Yuanchun |
| (Hunan University of Chinese Medicine，Changsha 410208，Hunan，China;Dianjiang Hospital of Traditional Chinese Medicine，Chongqing 408300，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Xianrong Yangjing Zhongyu decoction in the treatment of polycystic ovary syndrome (PCOS) with kidney Yin deficiency.Methods：A total of 60 patients with PCOS with kidney Yin deficiency were divided into treatment group and control group using a random number table，with 30 patients in each group.The patients in the treatment group were given Xianrong Yangjing Zhongyu decoction，and those in the control group were given Diane-35.Both groups were treated for three menstrual cycles，and then the two groups were compared in terms of follicular development，ovulation，clinical outcome，and changes in serum sex hormones.Results：There was a significant difference in overall response rate between the treatment group and the control group (90.00% vs 73.33%，P<0.05).Both groups had significant changes in traditional Chinese medicine syndrome score，ovulation，serum levels of testosterone and luteinizing hormone，and luteinizing hormone/follicle-stimulating hormone ratio after treatment，and there were significant differences in these indices between the two groups after treatment (P<0.05).Compared with the control group，the treatment group had significantly better improvements in menstrual cycle，menstrual volume，and follicular development after treatment (P<0.05).Conclusion：Xianrong Yangjing Zhongyu decoction has a marked clinical effect and good safety in the treatment of PCOS with kidney Yin deficiency and can regulate the levels of sex hormones，improve clinical symptoms，and promote follicular development and ovulation. |
| Key words: polycystic ovary syndrome kidney Yin deficiency traditional Chinese medicine treatment Xianrong Yangjing Zhongyu decoction |
