| 摘要: |
| 目的：观察柴胡陷胸汤加减联合美托洛尔治疗痰热瘀阻型冠心病合并室性期前收缩的临床疗效。方法：选取痰热瘀阻型冠心病合并室性期前收缩患者61例，随机分为治疗组31例和对照组30例。2组均行冠心病基础治疗，对照组另加美托洛尔治疗，治疗组在对照组基础上配合柴胡陷胸汤加减治疗，比较2组治疗前后综合疗效、室性期前收缩频率、中医证候积分及不良反应。结果：总有效率治疗组为93.55%，对照组为73.33%，2组比较，差异有统计学意义（P＜0.05）；2组室性期前收缩频率、中医证候积分改善治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P＜0.05）；2组不良反应发生率比较，差异无统计学意义（P＞0.05）。结论：柴胡陷胸汤加减联合美托洛尔治疗痰热瘀阻型冠心病合并室性期前收缩疗效优于单用美托洛尔。 |
| 关键词: 冠心病 室性期前收缩 痰热瘀阻证 中西医结合疗法 柴胡陷胸汤 美托洛尔 |
| DOI： |
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| Clinical effect of integrated traditional Chinese and Western medicine therapy in treatment of coronary heart disease with phlegm-heat and blood stasis syndrome complicated by premature ventricular contraction：An analysis of 31 cases |
| HE Huimin,XIE Haibo |
| (Hunan University of Chinese Medicine，Changsha 410208，Hunan，China;The First Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410007，Hunan，China) |
| Abstract: |
| Objective：To investigate the clinical effect of Chaihu Xianxiong decoction combined with metoprolol in the treatment of coronary heart disease with phlegm-heat and blood stasis syndrome complicated by premature ventricular contraction.Methods：A total of 61 patients with coronary heart disease with phlegm-heat and blood stasis syndrome complicated by premature ventricular contraction were randomly divided into treatment group with 31 patients and control group with 30 patients.The patients in the control group were given basic treatment of coronary heart disease combined with metoprolol，and those in the treatment group were given Chaihu Xianxiong decoction in addition to the treatment in the control group.The two groups were compared in terms of clinical outcome，frequency of premature ventricular contraction，traditional Chinese medicine (TCM) syndrome score，and adverse events.Results：There was a significant difference in overall response rate between the treatment group and the control group (93.55% vs 73.33%，P<0.05).Both groups had significant improvements in frequency of premature ventricular contraction and TCM syndrome score after treatment (P<0.05)，and there were significant differences in the two indices between the two groups after treatment (P<0.05).There was no significant difference in the incidence rate of adverse events between the two groups (P>0.05).Conclusion：Chaihu Xianxiong decoction combined with metoprolol has a better clinical effect than metoprolol alone in the treatment of coronary heart disease with phlegm-heat and blood stasis syndrome complicated by premature ventricular contraction. |
| Key words: coronary heart disease premature ventricular contraction phlegm-heat and blood stasis syndrome integrated traditional Chinese and Western medicine therapy Chaihu Xianxiong decoction metoprolol |
