| 摘要: |
| 心脑血管疾病是当前全球范围内危害人类健康的主要疾病之一，其发生发展与血脂异常密切相关。血脂异常作为该类疾病重要的可干预危险因素，其代谢过程已被证实具有多周期的时间节律特性。本文基于现代时间生物学与中医学理论，分别从昼夜节律、子午流注、四季节律及五运六气4个方面，阐述脂质代谢与时间节律之间的内在联系，旨在为血脂异常的因时防治提供理论依据，并推动精准医疗的临床实践。 |
| 关键词: 血脂异常 时间医学 子午流注 四时阴阳 五运六气 |
| DOI： |
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| Research advances in chronomedicine in treatment of dyslipidemia |
| LI Bingye,HONG Jun |
| (The Fourth Clinical Medical College of Xinjiang Medical University, Urumqi 830000, Xinjiang, China;Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University, Urumqi 830000, Xinjiang, China) |
| Abstract: |
| Cardiovascular and cerebrovascular diseases are among the major diseases threatening human health globally, and their development and progression are closely associated with dyslipidemia. Dyslipidemia is an important modifiable risk factor for such diseases, and studies have confirmed that the metabolic process of dyslipidemia has the characteristic of multi-period circadian rhythm. Based on modern chronobiology and traditional Chinese medicine theory, this article elaborates on the intrinsic relationship between lipid metabolism and time rhythms from the four aspects of circadian rhythm, midnight-midday ebb flow, seasonal rhythm, and five evolutive phases and six climatic factors, in order to provide a theoretical basis for time-based prevention and treatment of dyslipidemia and promote the clinical practice of precision medicine. |
| Key words: dyslipidemia chronomedicine midnight-midday ebb flow four seasons and Yin-Yang five evolutive phases and six climatic factors |
