| 摘要: |
| 目的:基于中医传承辅助平台分析穴位贴敷治疗腰椎间盘突出症(lumbar disc herniation,LDH)的用药与选穴规律。方法:检索中国知网、万方数据和维普中文科技期刊数据库2015年1月1日至2025年1月1日收录的穴位贴敷治疗LDH的相关临床文献,经筛选、规范化及双人核对后建立数据库,采用中医传承辅助平台(V3.5)进行药物和腧穴频次、药物性味归经及功效分析,以及药物和腧穴关联规则及聚类分析。结果:共纳入文献108篇,涉及中药177味,腧穴60个,其中使用频率较高的中药以没药、红花、川芎、草乌和细辛为主;药性以温、平、寒为主,药味以辛、苦、甘为主,归经以肝、脾、心经为主;功效以活血化瘀、祛风湿、补虚、解表及温里为主;关联规则中置信度最高的为“乳香→没药”,聚类分析共演化出3个核心组合。贴敷选穴以肾俞、阿是穴、环跳、腰阳关、委中为主;“肾俞,阿是穴→腰阳关”“环跳,委中→肾俞”为核心关联规则,并可形成 6 个聚类组合。结论:穴位贴敷治疗LDH的用药以活血化瘀、祛风除湿和温经通络治标,兼用补虚药兼顾肝肾亏虚,选穴兼顾腰部局部取穴、循经远取与补肾强腰。 |
| 关键词: 腰椎间盘突出症 穴位贴敷 选穴 用药 中医传承辅助平台 数据挖掘 |
| DOI: |
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| Medication and acupoint selection rules of acupoint application in treatment of lumbar disc herniation based on the Traditional Chinese Medicine Inheritance Support System |
| LUO Yuying,CHEN Xiaohong,LIN Jing,LI Xiufen |
| (Fangchenggang Hospital of Traditional Chinese Medicine, Fangchenggang 538000, Guangxi, China;The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, Guangxi, China) |
| Abstract: |
| Objective: To investigate the medication and acupoint selection rules of acupoint application in the treatment of lumbar disc herniation (LDH) based on the Traditional Chinese Medicine Inheritance Support System. Methods: CNKI, Wanfang Data, and VIP databases were searched for clinical articles on acupoint application for the treatment of LDH published from January 1, 2015 to January 1, 2025. A database was established after screening, standardization, and double-checking, the Traditional Chinese Medicine Inheritance Support System (V3.5) was used to analyze the frequency of drugs and acupoints and the nature, taste, meridian tropism, and function of drugs, as well as association rule analysis and cluster analysis of drugs and acupoints. Results: A total of 108 articles were included, involving 177 traditional Chinese medicine (TCM) drugs and 60 acupoints. High-frequency TCM drugs mainly included myrrh, Carthamus tinctorius, Rhizoma Chuanxiong, kusnezoff monkshood root, and as arum; most drugs had a warm, neutral or cold nature and a pungent, bitter, or sweet taste and mainly entered the liver, spleen, and heart meridians. The main functions of TCM drugs included activating blood and resolving stasis, dispelling wind-damp, tonifying deficiency,expelling exterior pathogens , and warming the interior. The association rule with the highest degree of confidence was “frankincense→myrrh”, and the cluster analysis obtained three core combinations. The acupoints selected for acupoint application mainly included Shenshu, Ashi point, Huantiao, Yaoyangguan, and Weizhong, with the core association rules of “Shenshu, Ashi point→Yaoyangguan” and “Huantiao, Weizhong→Shenshu”, and 6 cluster combinations were formed. Conclusion: For acupoint application in the treatment of LDH, the drugs for activating blood and resolving stasis, dispelling wind-damp, and warming the meridians and dredging collaterals are mainly used for the treatment of manifestations, and deficiency-tonifying drugs are used to address deficiency of liver and kidney. Acupoint selection takes into account local acupoints in the lumbar region, distal acupoints along the meridians, and acupoints for strengthening the kidney and reinforcing the lower back. |
| Key words: lumbar disc herniation acupoint application acupoint selection medication Traditional Chinese Medicine Inheritance Support System data mining |