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甲泼尼龙片联合血安1号方治疗气不摄血型原发免疫性血小板减少症30例
陈慧玲,钟新林
0
(湖南中医药大学,湖南 长沙,410208;湖南中医药大学附属衡阳医院,湖南 衡阳,421001)
摘要:
目的:观察甲泼尼龙片联合血安1号方治疗气不摄血型原发免疫性血小板减少症(ITP)的临床疗效。方法:选取气不摄血型ITP患者60 例,将其随机分为治疗组和对照组,每组各30 例。对照组予甲泼尼龙片治疗,治疗组在对照组基础上联合血安1号方治疗,2组均以1周为1个疗程,治疗4个疗程后比较2组治疗前后外周血小板计数水平、中医证候积分,并评价临床疗效。结果:总有效率治疗组为80.00%(24/30),对照组为63.33%(19/30),2组比较,差异有统计学意义(P<0.05);2组外周血小板计数水平、中医证候积分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:采用甲泼尼龙片联合血安1号方治疗气不摄血型ITP比单用甲泼尼龙片疗效更好,可推广使用。
关键词:  原发免疫性血小板减少症  气不摄血证  血安1号方  甲波尼龙片
DOI:
Clinical effect of methylprednisolone tablets combined with Xue’an No.1 prescription in treatment of primary immune thrombocytopenia with Qi failing to control blood:An analysis of 30 cases
CHEN Huiling,ZHONG Xinlin
(Hunan University of Chinese Medicine,Changsha 410208,Hunan,China;Hengyang Hospital Affiliated to Hunan University of Chinese Medicine,Hengyang 421001,Hunan,China)
Abstract:
Objective: To investigate the clinical effect of methylprednisolone tablets combined with Xue’an No.1 prescription in the treatment of primary immune thrombocytopenia (ITP) with Qi failing to control blood.Methods: A total of 60 ITP patients with Qi failing to control blood were randomly divided into treatment group and control group,with 30 patients in each group.The patients in the control group were given methylprednisolone tablets,and those in the treatment group were given Xue’an No.1 prescription in addition to the treatment in the control group.Each course of treatment was 1 week,and both groups were treated for 4 courses.The two groups were compared in terms of peripheral blood platelet count and traditional Chinese medicine (TCM) syndrome score,and clinical outcome was evaluated.Results: There was a significant difference in overall response rate between the treatment group and the control group [80.00% (24/30) vs 63.33% (19/30),P<0.05].After treatment,both groups had significant changes in peripheral blood platelet count and TCM syndrome score,and there were significant differences in these indicators between the two groups (P<0.05).Conclusion: Methylprednisolone tablets combined with Xue’an No.1 prescription has a better clinical effect than methylprednisolone tablets alone in the treatment of ITP with Qi failing to control blood and thus holds promise for clinical application.
Key words:  primary immune thrombocytopenia  Qi failing to control blood  Xue’an No.1 prescription  methylprednisolone tablets

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