| 摘要: |
| 目的：基于数据挖掘探讨孙达武教授治疗腰痛的用药规律。方法：收集孙教授治疗腰痛患者的医案，采用中医传承辅助平台（V2.5）进行中药使用频次分析、四气五味归经、聚类分析等数据挖掘，分析其用药规律，并挖掘药物核心组合和提取新处方。结果：共纳入病案158则，处方158首，涉及药物61味。中药使用频次排名前10位的依次为杜仲、甘草、狗脊、续断、延胡索、牛膝、骨碎补、独活、透骨草、鸡血藤。中药功效以强筋壮骨类、活血止痛类为主。药性以温、平、寒为主，药味以苦、甘、辛为主，归经以肝、肾、脾经为主。根据关联规则和聚类分析得到高频药物组合12个，新方3首。结论：孙教授治疗腰痛强调三因制宜，以补肾活血为基本思路，注重顾护脾胃，以补益肝肾、强筋壮骨、活血化瘀、祛风除湿为治疗原则。 |
| 关键词: 腰痛 数据挖掘 用药规律 孙达武 |
| DOI： |
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| Medication rule of Sun Dawu in treatment of lumbago：A study based on data mining |
| CAI Zhefu,YE Xinyu,ANG Rencheng |
| (Hunan University of Chinese Medicine，Changsha 410208，Hunan，China) |
| Abstract: |
| Objective：To investigate the medication rule of Professor Sun Dawu in the treatment of lumbago based on data mining.Methods：Medical records were collected from the patients with lumbago who were treated by Professor Sun，and Traditional Chinese Medicine Inheritance Support System (V2.5) was used to perform data mining，including the frequency of use of traditional Chinese medicine (TCM) drugs，nature/taste/meridian entry，and cluster analysis，to analyze related medication rules and obtain core drug combinations and new prescriptions.Results：A total of 158 cases were included，involving 158 prescriptions and 61 TCM drugs.The top 10 drugs in terms of frequency of use were Eucommia ulmoides，Radix Glycyrrhizae，Rhizoma Cibotii，teasel root，Rhizoma Corydalis，Radix Achyranthis Bidentatae，Rhizoma Drynariae，Angelica pubescens，Herba Speranskiae Tuberculatae，and Spatholobi Caulis.The main functions of the TCM drugs included strengthening tendons and bones，activating blood，and relieving pain.Most drugs were warm，neutral or cold in nature and had a bitter，sweet or pungent taste，and they mainly entered the liver，kidney，and spleen meridians.The association rule analysis and the cluster analysis obtained 12 high-frequency drug combinations and 3 new prescriptions.Conclusion：In the treatment of lumbago，Professor Sun emphasizes the treatment in accordance with the patient’s individuality，seasonal conditions，and local conditions，applies kidney-tonifying and blood-activating therapy as the main idea，and focuses on the care of the spleen and the stomach，with the treatment principles of tonifying liver and kidney，strengthening tendons and bones，activating blood and resolving stasis，and dispelling pathogenic wind and removing dampness. |
| Key words: lumbago data mining medication rule Sun Dawu |
