| 摘要: |
| 目的：基于数据挖掘探讨中药治疗肛门坠胀的用药规律。方法：收集中国知网(CNKI)、维普中文科技期刊数据库(VIP)、万方数据(WANFANG DATA)中自建库至2023年5月31日有关中医药治疗肛门坠胀的文献，根据纳入及排除标准进行筛选，建立数据库，采用聚类分析、关联规则等方法进行数据挖掘，并对药物频次、类别、性味归经、聚类及关联规则进行分析。结果：最终纳入文献45篇，方剂49首，中药139味，累计用药频次501次，使用频次较高的中药为当归、升麻、柴胡、炙甘草、白术等，功效以补虚、清热、理气、活血化瘀、利水渗湿为主，药性多为温、寒、平，药味多为苦、甘、辛，归经以脾、肝、胃经为主；挖掘出18个关联规则，聚类分析可分为4类，涉及秦艽苍术汤、补中益气汤等。结论：中药治疗肛门坠胀以补益中气为核心，随症治以清热利湿、活血化瘀、利水渗湿之法。 |
| 关键词: 肛门坠胀 中医药 数据挖掘 用药规律 |
| DOI： |
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| Medication rule of traditional Chinese medicine in treatment of anal pendant expansion：A study based on data mining |
| ZHAO Yuan,ZENG Chaoqun,HU Xiangdang |
| (The Second Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410005，Hunan，China) |
| Abstract: |
| Objective：To investigate the medication rule of traditional Chinese medicine (TCM) in the treatment of anal pendant expansion based on data mining. Methods：CNKI，VIP，and Wanfang Data were searched for articles on TCM treatment of anal pendant expansion published up to May 31st，2023，which were screened based on inclusion and exclusion criteria to establish a database. The methods such as cluster analysis and association rule analysis were used for data mining，and the drugs were analyzed in terms of frequency，category，nature/taste/meridian entry，cluster analysis，and association rule analysis. Results：A total of 45 articles were included，involving 49 prescriptions and 139 TCM drugs，with a total frequency of 501 times. The TCM drugs with a relatively high frequency of use included Angelica sinensis，Rhizoma Cimicifugae，Bupleurum chinense，Radix Glycyrrhizae Preparata，and Atractylodes macrocephala Koidz.，and the functions mainly included deficiency-tonifying herbs，heat-clearing drugs，Qi-regulating drugs，blood-activating and stasis-resolving drugs，and diuresis-inducing and dampness-draining drugs. Most drugs were warm，cold or neutral in nature and had a bitter，sweet，and pungent taste，and they mainly entered the spleen，liver，and stomach meridians. A total of 18 association rules were obtained，and the drugs were clustered into 4 categories based on the cluster analysis，involving Gentiana macrophylla-Rhizoma Atractylodis decoction and Buzhong Yiqi decoction. Conclusion：Tonifying middle Qi is the core of TCM treatment of anal pendant expansion，and the methods such as heat-clearing and diuresis-inducing therapy，blood-activating and stasis-resolving therapy，and diuresis-inducing and dampness-draining therapy are used based on symptoms. |
| Key words: anal pendant expansion traditional Chinese medicine data mining medication rule |
