| 摘要: |
| 目的：基于数据挖掘探析《证治准绳》中痞满治疗的用药规律。方法：搜索整理《证治准绳》中关于中药治疗痞满的医案，运用古今医案云平台（V2.3.8）采用频次计算、关联规则、聚类分析等方法进行统计分析。结果：纳入处方86首，涉及中药136味，药物总频次为752次，排前10位的中药有甘草、陈皮、半夏、人参、木香、茯苓、白术、厚朴、枳实、青皮。药性以温性为主，药味以辛、苦、甘味为主，归经以脾、胃、肺经为主。排前3位的功效为燥湿化痰、清热解毒、补脾益气。药物关联规则分析得出常用药对19对，聚类分析得出核心药物组合4组，复杂网络分析获得治疗痞满的核心药物为甘草、陈皮、人参、茯苓、半夏、木香、厚朴、白术、干姜及青皮。结论：《证治准绳》中痞满的主要治法为益气健脾、温中补虚、理气燥湿、消食除胀，并注重燥湿化痰、清热解毒、补脾益气类药物的运用。 |
| 关键词: 痞满 《证治准绳》 数据挖掘 用药规律 |
| DOI： |
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| Medication rule in the treatment of stuffiness and fullness in Standards for Diagnosis and Treatment：A study based on data mining |
| KANG Yanhong,WANG Jinxing,FANG Fang |
| (Hunan University of Chinese Medicine，Changsha 410208，Hunan，China) |
| Abstract: |
| Objective：To investigate the medication rule in the treatment of stuffiness and fullness in Standards for Diagnosis and Treatment based on data mining.Methods：The medical records for the traditional Chinese medicine treatment of stuffiness and fullness in Standards for Diagnosis and Treatment were collected，and with the help of the ancient and modern medical case cloud platform，the methods such as frequency calculation，association rule analysis，and cluster analysis were used for statistical analyses.Results：A total of 86 prescriptions were included，involving 136 traditional Chinese medicine drugs.The total frequency of drugs was 752，and the top 10 drugs were Radix Glycyrrhizae，tangerine peel，Pinellia ternata，Panax ginseng，Saussurea costus，Poria cocos，Atractylodes macrocephala Koidz.，Magnolia officinalis，Fructus Aurantii Immaturus，and Pericarpium Citri Reticulatae Viride.Most drugs were warm in nature and had a pungent，bitter or sweet taste，and they mainly entered the spleen，stomach，and lung meridians.The top three functions were dampness-drying and phlegm-eliminating，heat-clearing and detoxicating，and spleen-tonifying and Qi-tonifying.The association rule analysis obtained 19 commonly used drug combinations，the cluster analysis obtained 4 groups of core drugs，and the complex network analysis showed that the core drugs for the treatment of stuffiness and fullness were Radix Glycyrrhizae，tangerine peel，Panax ginseng，Poria cocos，Pinellia ternata，Saussurea costus，Magnolia officinalis，Atractylodes macrocephala Koidz.，dried ginger，and Pericarpium Citri Reticulatae Viride.Conclusion：The main treatment methods for stuffiness and fullness Standards for Diagnosis and Treatment are benefiting Qi and strengthening the spleen，warming middle-Jiao and tonifying deficiency，regulating Qi and drying dampness，and promoting digestion and eliminating flatulence，with emphasis on the application of dampness-drying and phlegm-eliminating drugs，heat-clearing and detoxicating drugs，and spleen-tonifying and Qi-tonifying drugs. |
| Key words: stuffiness and fullness Standards for Diagnosis and Treatment data mining medication rule |
