| 摘要: |
| 目的：基于中医传承辅助平台，分析现代名中医治疗小儿遗尿症的用药规律，以期传承其学术经验。方法：将湖南中医药大学线上图书馆中的读秀数据库作为检索来源，收集整理现代名中医治疗小儿遗尿症的医案，录入中医传承辅助平台（V2.5），进行用药规律研究。结果：共收集处方220首，涉及中药.213味，总用药频次2513次，用药以补气、收敛、补阳为主，药性多温、平，药味多甘、辛、苦味，主归肾、脾经。根据病机分证论治，下元虚寒证的高频用药为益智仁、桑螵蛸、金樱子、乌药、覆盆子、补骨脂、石菖蒲、茯苓；肺脾气虚证的高频用药为益智仁、桑螵蛸、黄芪、党参、白术、山药；心肾不交证的高频用药为益智仁、桑螵蛸、山药、山茱萸、茯苓；肝经湿热证的高频用药为柴胡、黄芩、生地黄、甘草。基于平台挖掘出核心药物组合20条，得出新方10首。结论：治疗小儿遗尿症，现代名中医重视脏腑辨证和虚实辨证，虚证温补肾阳，多选用益智仁和桑螵蛸温肾止遗；实证则喜用柴胡、黄芩疏肝清热。 |
| 关键词: 小儿遗尿症 数据挖掘 现代名中医 用药规律 文献研究 |
| DOI： |
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| Medication rule and academic experience of modern famous TCM doctors in treatment of pediatric enuresis：A study based on data mining |
| ZHOU Xiaofeng,HAO Xingyu,LUO Xuan |
| (Hunan University of Chinese Medicine，Changsha 410208，Hunan，China) |
| Abstract: |
| Objective：To investigate the medication rule of modern famous TCM doctors in the treatment of pediatric enuresis based on Traditional Chinese Medicine Inheritance Support System，and to inherit their academic experience.Methods：Duxiu Database in the online library of Hunan University of Chinese Medicine was searched for the medical records of modern famous TCM doctors in the treatment of pediatric enuresis，and these medical records were imported into Traditional Chinese Medicine Inheritance Support System （V2.5） to analyze the medication rule.Results：A total of 220 prescriptions were collected，involving 213 TCM drugs，with a total frequency of 2513，and Qi-tonifying，astringent，and Yang-tonifying drugs were mainly used.Most drugs were warm or neutral in nature and had a sweet，pungent or bitter taste，and they mainly entered the kidney and spleen meridians.Treatment based on pathogenesis and syndrome showed that Sharpleaf Galangal Fruit，mantis egg-case，Rosa laevigata，Lindera aggregata，Rubi Fructus，Fructus Psoraleae，Rhizoma Acori graminei，and Poria cocos were the high-frequency drugs for the syndrome of vacuity cold of the lower origin；Sharpleaf Galangal Fruit，mantis egg-case，Astragalus membranaceus，Codonopsis pilosula，Atractylodes macrocephala Koidz.，and Dioscorea opposite were the high-frequency drugs for the syndrome of lung-spleen Qi deficiency；Sharpleaf Galangal Fruit，mantis egg-case，Dioscorea opposita，Comus officinalis，and Poria cocos were the high-frequency drugs for the syndrome of disharmony between heart and kidney；Bupleurum chinense，Scutellaria baicalensis，Radix Rehmanniae，and Radix Glycyrrhizae were the high-frequency drugs for liver channel damp-heat syndrome.Data mining based on the platform obtained 20 core drug combinations and 10 new prescriptions.Conclusion：In the treatment of pediatric enuresis，modern famous TCM doctors emphasize syndrome differentiation of viscera and bowels and syndrome differentiation of deficiency and excess.Warming and tonifying kidney Yang is the main treatment method for deficiency syndrome，and Sharpleaf Galangal Fruit and mantis egg-case are mainly used for warming the kidney and checking enuresis；for excess syndrome，Bupleurum chinense and Scutellaria baicalensis are mainly used for soothing the liver and clearing heat. |
| Key words: pediatric enuresis data mining modern famous TCM doctors medication rule literature research |
