| 摘要: |
| 目的：观察自拟消痤汤联合红光照射治疗瘀热互结型痤疮的临床疗效。方法：将80 例瘀热互结型痤疮患者随机分为治疗组和对照组，每组各40 例。治疗组采用内服消痤汤、外用红光照射治疗，对照组予以内服多西环素和西咪替丁、外用0.1%阿达帕林凝胶外涂治疗，2组疗程均为4周。比较2组综合疗效、皮疹情况及不良反应发生率。结果：治疗组治疗2周及4周的总有效率分别为67.5%（27/40）、90.0%（36/40），明显高于对照组的55.0%（22/40）、75.0%（30/40），差异均有统计学意义（P<0.05）。治疗后，2组皮损积分均较治疗前下降，且治疗组的积分下降幅度大于对照组，差异均有统计学意义（P<0.05）。不良反应发生率治疗组为2.5%（1/40），对照组为10.0%（4/40），2组比较，差异无统计学意义（P>0.05）。结论：消痤汤联合红光照射治疗瘀热互结型痤疮疗效显著，值得临床推广应用。 |
| 关键词: 痤疮 瘀热互结证 消痤汤 红光照射 |
| DOI： |
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| Clinical effect of Xiaocuo decoction combined with red light irradiation in treatment of acne with intermingled stasis and heat：An analysis of 40 cases |
| PENG Wubin,CAI Yuhao |
| (Yunfu Hospital of Traditional Chinese Medicine，Yunfu 527300，Guangdong，China) |
| Abstract: |
| Objective：To investigate the clinical effect of self-made Xiaocuo decoction combined with red light irradiation in the treatment of acne with intermingled stasis and heat.Methods：A total of 80 patients with acne with intermingled stasis and heat were randomly divided into treatment group and control group，with 40 patients in each group.The patients in the treatment group were given oral administration of Xiaocuo decoction and external application of red light irradiation，and those in the control group were given oral administration of doxycycline and cimetidine and external application of 0.1% adapalene gel；the course of treatment was 4 weeks for both groups.The two groups were compared in terms of overall response，skin rash，and incidence rate of adverse reactions.Results：At weeks 2 and 4 of treatment，the treatment group had a significantly higher overall response rate than the control group ［week 2：67.5%（27/40）vs 55.0%（22/40），P<0.05；week 4：90.0%（36/40） vs 75.0% （30/40），P<0.05］.After treatment，both groups had a significant reduction in skin lesion score，and the treatment group had a significantly greater reduction than the control group （P<0.05）.There was no significant difference in the incidence rate of adverse reactions between the treatment group and the control group ［2.5%（1/40）vs 10.0%（4/40），P>0.05］.Conclusion：Xiaocuo decoction combined with red light irradiation has a marked clinical effect in the treatment of acne with intermingled stasis and heat and thus holds promise for clinical application. |
| Key words: acne intermingled stasis and heat Xiaocuo decoction red light irradiation |
