| 摘要: |
| 目的：探讨卒中后认知功能障碍（PSCI）与缺血性卒中中医证型的相关性。方法：将急性缺血性脑卒中患者109 例根据蒙特利尔认知评估量表（MoCA）得分情况分为认知功能正常（NCI）组和认知功能障碍（CI）组。对比分析2组患者卒中后认知功能障碍发生的相关因素以及与中医证型的关联性。结果：CI组平均年龄、平均神经功能缺损（NIHSS）评分高于NCI组，差异具有统计学意义（P＜0.05）。2组在糖尿病、颅内动脉狭窄和梗死病灶方面比较，NCI组低于CI组。在中医证型分布上，NCI组的风火上扰证例数多于CI组，而CI组的气虚血瘀证和阴虚风动证例数多于NCI组，差异具有统计学意义（P＜0.05）。气虚血瘀证额叶梗死部位多于痰热腑实证（P<0.01）与风火上扰证（P<0.05）；风火上扰证颞叶梗死部位多于气虚血瘀证（P<0.05）和风痰瘀阻证（P<0.05）；风痰瘀阻证枕叶梗死部位多于气虚血瘀证（P<0.05）和痰热腑实证（P<0.05）；其余部位梗死与证型之间差异无统计学意义（P>0.05）。结论：中医证型为阴虚风动证和气虚血瘀证的急性缺血性脑卒中患者更易发生PSCI。 |
| 关键词: 卒中后认知功能障碍 中医证型 梗死病灶部位 |
| DOI： |
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| Association of post-stroke cognitive impairment with traditional Chinese medicine syndrome types |
| YU Wenjing,YANG Xiongjie |
| (Professional Postgraduate Training Base of Wuhu Hospital of Traditional Chinese Medicine，Anhui University of Chinese Medicine，Wuhu 241000，Anhui，China;Wuhu Hospital of Traditional Chinese Medicine，Wuhu 241000，Anhui，China) |
| Abstract: |
| Objective：To investigate the association of post-stroke cognitive impairment(PSCI) with traditional Chinese medicine (TCM) syndrome types of ischemic stroke.Methods：According to the Montreal Cognitive Assessment score，109 patients with acute ischemic stroke were divided into non-cognitive impairment group (NCI group) and cognitive impairment group (CI group).The two groups were compared in terms of the factors for PSCI and their association with TCM syndrome types.Results：The CI group had significantly higher mean age and mean National Institutes of Health Stroke Scale score than the NCI group (P＜0.05).The NCI group had lower degrees of diabetes，intracranial arterial stenosis，and infarct lesion than the CI group.As for the distribution of TCM syndrome types，the NCI group had a significantly higher number of cases with upward disturbance of wind-fire than the CI group，and the CI group had a significantly higher number of cases with Qi deficiency and blood stasis syndrome orsyndrome of stirring wind due to Yin deficiency than the NCI group (P＜0.05).The patients with Qi deficiency and blood stasis syndrome had a significantly higher proportion of patients with infarction in the frontal lobe than those with excessive Fu-viscera caused by phlegm-heat (P<0.01) or upward disturbance of wind-fire (P<0.05)；the patients with upward disturbance of wind-fire had a significantly higher proportion of patients with infarction in the temporal lobe than those with Qi deficiency and blood stasis syndrome (P<0.05) or wind-phlegm stasis syndrome (P<0.05)；the patients with wind-phlegm stasis syndrome had a significantly higher proportion of patients with infarction in the occipital lobe than those with Qi deficiency and blood stasis syndrome (P<0.05) or excessive Fu-viscera caused by phlegm-heat (P<0.05)；there was no significant difference in infarction location between the patients with the other syndromes (P>0.05).Conclusion：The patients with acute ischemic stroke who have the TCM syndrome type of stirring wind due to Yin deficiency or Qi deficiency and blood stasis syndrome tend to develop PSCI. |
| Key words: post-stroke cognitive impairment traditional Chinese medicinesyndrome type infarction location |
