| 摘要: |
| 目的：观察中医序贯疗法治疗儿童重症监护室（PICU）喘息性肺炎的临床疗效及对IgE水平的影响。方法：将60 例PICU喘息性肺炎患儿随机分为治疗组和对照组,每组各30 例。对照组采用西医常规治疗,疗程为14d;治疗组在对照组基础上采用中医序贯疗法,第1～7天服用小青龙汤治疗,第8～14天服用六君子汤加味治疗。比较2组综合疗效、喘息消失时间、平均住院天数,治疗后第8天、15天及1个月血清IgE水平,随访6个月,比较2组复发率。结果：总有效率治疗组为93.3%（28/30）,对照组为76.7%（23/30）,2组比较,差异有统计学意义（P＜0.05）。2组IgE治疗后第8天、第15天、1个月组内比较,差异均有统计学意义（P＜0.01）,治疗后第15天、1个月组间比较,差异亦有统计学意义（P＜0.01）。2组喘息消失时间、平均住院天数、复发率比较,差异均有统计学意义（P＜0.01或P<0.05）。结论：中医序贯疗法能有效改善PICU喘息性肺炎患儿喘息症状,降低IgE水平,缩短住院时间,降低复发率,疗效显著。 |
| 关键词: 喘息性肺炎 儿童重症监护室 中医序贯疗法 小青龙汤 六君子汤 |
| DOI： |
|
|
| Clinical effect of traditional Chinese medicine sequential therapy in treatment of children with asthmatic pneumonia admitted to the pediatric intensive care unit and its effect on IgE |
| PENG Nanzhi,ZENG Caixiu,YANG Xiaoli |
| (Xiangtan Maternal and Child Health Hospital,Xiangtan 411104,Hunan,China) |
| Abstract: |
| Objective:To investigate the clinical effect of traditional Chinese medicine (TCM) sequential therapy in the treatment of children with asthmatic pneumonia admitted to the pediatric intensive care unit (PICU) and its effect on the level of IgE.Methods：A total of 60 children with asthmatic pneumonia who were admitted to the PICU were randomly divided into treatment group and control group,with 30 patients in each group.The patients in the control group were given conventional Western medicine treatment for 14 days,and those in the treatment group were given TCM sequential therapy with Xiaoqinglong decoction on days 1-7 and Jiawei Liujunzi decoction on days 8-14 in addition to the treatment for the control group.The two groups were compared in terms of overall response,time to the disappearance of wheezing,mean length of hospital stay,and serum level of IgE on days 8 and 15 and at 1 month after treatment,and both groups were followed up for 6 months to compare recurrence rate.Results：There was a significant difference in overall response rate between the treatment group and the control group ［93.3% (28/30) vs 76.7% (23/30),P＜0.05］.Both groups had a significant change in IgE on days 8 and 15 and at 1 month after treatment (P＜0.01),and there was a significant difference in IgE between the two groups on day 15 and at 1 month after treatment (P＜0.01).There were significant differences between the two groups in time to the disappearance of wheezing,mean length of hospital stay,and recurrence rate (P＜0.01 or P＜0.05).Conclusion：TCM sequential therapy has a marked clinical effect in children with asthmatic pneumonia admitted to the PICU and can effectively improve the symptom of wheezing,reduce the level of IgE,shorten the length of hospital stay,and reduce recurrence rate. |
| Key words: asthmatic pneumonia pediatric intensive care unit traditional Chinese medicine sequential therapy Xiaoqinglong decoction Liujunzi decoction |
