| 摘要: |
| 目的：研究肝硬化食管静脉曲张套扎术（Endoscopic Variceal Ligation，EVL）后患者的中医证型分布规律及其相关因素，为中医药临床治疗本病提供基础理论指导。方法：采用临床流行病学研究方法，对100例肝硬化食管静脉曲张患者经电子内镜下行套扎术，术后4周对患者中医证型分布规律及其相关要素进行分析。结果：EVL后患者中医证型以肝肾阴虚证、脾肾阳虚证为多见，而肝气郁结证为最少见；男性患者证型主要集中在脾肾阳虚证、肝肾阴虚证（P<0.05），女性患者证型主要集中在肝肾阴虚证、血瘀阻络证（P<0.05）；肝肾阴虚证与51～60岁年龄呈正相关，脾肾阳虚证与61～70岁年龄呈正相关；术后8个月，以肝肾阴虚证、脾肾阳虚证为主，其中肝肾阴虚证明显多于其他各证，差异有统计学意义（P<0.05）；术后16个月，以肝肾阴虚证、瘀血阻络证、脾肾阳虚证为主，3个证型之间差异无统计学意义（P>0.05）；术后22个月，以瘀血阻络证、湿热蕴结证、水湿内阻证、脾肾阳虚证为主，4个证型之间差异无统计学意义（P>0.05）。在病程发展过程中，肝肾阴虚证比例随术后时间增加而减少（P<0.05）。 |
| 关键词: 肝硬化 食管胃底静脉曲张套扎术 中医证型 分布规律 |
| DOI： |
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| Distribution pattern of TCM syndrome types after esophageal variceal ligation for liver cirrhosis and related factors |
| PENG Zhuo-yu，,LI Rui-sheng，,CHEN Jing |
| (The First Affiliated Hospital of Guangxi University of Chinese Medicine，Nanning 530023，Guangxi，China;Guangxi University of Chinese Medicine，Nanning 530001，Guangxi，China) |
| Abstract: |
| Objective：To investigate the distribution pattern of traditional Chinese medicine（TCM） syndrome types after endoscopic esophageal variceal ligation（EVL） for liver cirrhosis and related factors，and to provide theoretical guidance for TCM treatment of this disease in clinical practice.Methods：A clinical epidemiological study was performed.Endoscopic EVL was performed for 100 cirrhotic patients with esophageal varices，and the distribution pattern of TCM syndrome types and related factors were analyzed at 4 weeks after surgery.Results：Syndrome of liver-kidney yin deficiency and syndrome of spleen-kidney yang deficiency were the most common TCM syndrome types after EVL，while stagnation of liver qi was the least common syndrome type.Male patients mainly had the syndrome types of spleen-kidney yang deficiency and liver-kidney yin deficiency（P<0.05），and female patients mainly had liver-kidney yin deficiency and blood stasis obstructing the collaterals（P<0.05）.Liver-kidney yin deficiency was positively correlated with the age of 51-60 years，and spleen-kidney yang deficiency was positively correlated with the age of 61-70 years.At 8 months after surgery，liver-kidney yin deficiency and spleen-kidney yang deficiency were major syndrome types，among which liver-kidney yin deficiency was the most common one（P<0.05）；at 16 months after surgery，liver-kidney yin deficiency，blood stasis obstructing the collaterals，and spleen-kidney yang deficiency were major syndrome types，and there was no significant difference between them（P>0.05）；at 22 months after surgery，blood stasis obstructing the collaterals，damp-heat accumulation，water dampness obstructing the interior，and spleen-kidney yang deficiency were major syndrome types，and there was no significant difference between them（P>0.05）.The proportion of patients with liver-kidney yin deficiency gradually decreased over time after surgery（P<0.05）. |
| Key words: liver cirrhosis esophageal variceal ligation TCM syndrome type distribution pattern |
